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  1. 27 Ιαν 2022 · Fetal fraction, an important parameter in the analysis of noninvasive prenatal screening results, is the proportion of fetal cell-free DNA present in the total maternal plasma cell-free DNA. It combines biological factors and bioinformatics algorithms to interpret noninvasive prenatal screening results and is an integral part of quality control.

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      A paradigm shift in noninvasive prenatal screening has been...

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      A paradigm shift in noninvasive prenatal screening has been...

  2. 10 Δεκ 2019 · Fetal fraction (FF) is the percentage of total maternal plasma cfDNA that is of fetoplacental origin [FF = fetal cfDNA/(fetal cfDNA + maternal cfDNA). It is therefore a function of both maternal and fetal cfDNA levels in the maternal plasma.

  3. 4 ημέρες πριν · Fetal fraction is the term given to the proportion of cfDNA belonging to the placenta found in the mother’s blood. In order to perform NIPT, there must be a minimum level of fetal fraction (a minimum amount of placental cfDNA).

  4. 9 Αυγ 2021 · The fraction of all DNA circulating in the mother’s blood that originates from the fetus is called the fetal fraction (FF), expressed as a percentage value. Researchers can exploit the differences between the fetal DNA and the mother’s DNA to estimate FF.

  5. 8 Δεκ 2022 · The ability to detect fetal chromosomal aneuploidies is directly related to a sample’s fetal to total DNA fraction, known as the fetal fraction (FF). The minimum FF is considered 4%, and the test result below 4% is uncertain due to low fetal fraction (LFF).

  6. 20 Ιουν 2023 · Fetal biometry is a test that measures the size of a fetus during pregnancy using ultrasound. It consists of several measurements that tell your pregnancy care provider how the fetus is growing for its gestational age and if there are signs of growth problems. It helps diagnose fetal growth disorders.

  7. 25 Οκτ 2012 · The fetal fraction decreased with increased maternal weight, it was lower in women of Afro-Caribbean origin than in Caucasians and increased with fetal crown–rump length, serum pregnancy-associated plasma protein-A, serum free β -human chorionic gonadotropin, smoking and trisomy 21 karyotype.

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