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Rochester is a city in southern Minnesota. It's the birthplace of renowned healthcare organization the Mayo Clinic. The complex includes the landmark 1928 Plummer Building.
There are 9 ways to get from Chicago to Rochester by plane, train, bus, or car. Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner. best. Fly Chicago O'Hare to Rochester. 4h 12m. $186–454. cheapest. Train, bus. 7h 14m. $42–162. Bus. 8h 55m. $64–139. Drive 348 mi. 5h 42m.
Directions to Rochester, MN
There are 9 ways to get from Chicago to Rochester, MN - stop 205, 6th St SW by plane, bus, car, or train. Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.
Step by step directions for your drive or walk. Easily add multiple stops, see live traffic and road conditions. Find nearby businesses, restaurants and hotels. Explore!
Driving directions to Rochester, MN including road conditions, live traffic updates, and reviews of local businesses along the way.