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Nausea, diarrhea, and abdominal pain were the most common side effects. Lubiprostone-stimulated secretion of CI ions via C1C2 channels was inhibited in vitro in T84 cell lines by methadone. As a result of these studies, lubiprostone is contraindicated in OIC associated with methadone use.
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The use of opioid medications on both an acute and chronic...
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18 Μαΐ 2017 · Abdominal pain and nausea were the most common adverse events reported; other adverse effects were diarrhea, hyperhidrosis, and vomiting. The FDA has approved 12 mg subcutaneous injection of methylnaltrexone for the treatment of OIC in patients taking opioids for chronic, non-cancer pain.
4 Ιουν 2021 · OIC and opioid-induced bowel dysfunction are well-recognised unwanted effects of treatment with opioid analgesics that can profoundly affect quality of life. OIC can be due to additional factors such as reduced mobility, a low-fibre diet, comorbidities, and concomitant medications.
24 Ιουλ 2023 · Acute Colonic Pseudo-obstruction (ACPO) is a cause of large intestinal dilation and obstruction without any physical transition point. It remains difficult to diagnose and treat. We review the recent updates on diagnosis and management of ACPO.
29 Απρ 2019 · Bowel obstruction is an important cause of morbidity and mortality accounting for nearly 30,000 deaths and more than $3 billion per year in direct medical costs; it is responsible for approximately 15% of hospital admissions for acute abdominal pain in the USA and ~ 20% of cases needing acute surgical care [ 1, 2 ].
15 Δεκ 2016 · Opioid-induced constipation (OIC) is the most frequently reported and persistent side effect in patients receiving opioids for analgesia . This review aims to evaluate the current understanding of OIBD and provide timely evidence-based recommendations for the management of patients affected by this condition. Methods. A search of the medical ...
27 Νοε 2020 · This article will review the GI side effects following treatments of radiation therapy, chemotherapy and immunotherapy. Radiotherapy-related enteritis.
