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  1. 15 Ιουν 2024 · Diagnosis. Because scleroderma can take so many forms and affect so many different areas of the body, it can be difficult to diagnose. After a thorough physical exam, your healthcare professional may suggest blood tests to check for elevated levels of certain antibodies made by the immune system.

  2. 15 Ιουν 2024 · Symptoms. Scleroderma symptoms vary from person to person, depending on which parts of the body are affected. Skin-related symptoms. Nearly everyone who has scleroderma experiences hardening and tightening of the skin. The first parts of the body to be affected are usually the fingers, hands, feet and face.

  3. 1 Απρ 2020 · Mayo Clinic doctors use state-of-the-art imaging modalities, including nailfold video capillaroscopy, for early detection of vascular changes that may help diagnose scleroderma and other scleroderma spectrum disorders, such as mixed connective tissue disease, dermatomyositis and others.

  4. Our approach is that patients with active diffuse skin disease without major organ disease have 3 treatment options: (1) follow with serial observations to define the severity and course of the disease in that in many the skin disease is mild and largely reversible; (2) institute traditional low-dose antimetabolite/immunosuppressive therapy (eg ...

  5. Therapy should be directed at the underlying cause. For lower gastrointestinal tract symptoms, a bowel regimen (eg, polyethylene glycol) for constipation and a trial of antibiotics for diarrhea may improve quality of life, and IBS medications may be helpful.

  6. 5 Απρ 2024 · Objectives: Identify early clinical manifestations and risk factors associated with systemic sclerosis to facilitate prompt diagnosis and intervention. Implement regular screening protocols for systemic sclerosis complications, including pulmonary function tests, echocardiography, and renal function assessments.

  7. 3 Νοε 2023 · Initial symptoms are non-specific and include fatigue, vague musculoskeletal complaints, diffuse swelling of hands, and Raynaud's phenomenon. Aetiology and pathogenesis are unknown. Disease course is variable, but the condition rarely subsides spontaneously.

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