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  1. 22 Μαΐ 2020 · The review concludes with an overview of future research needed to (1) understand how to personalize the care of systemic sclerosis–associated interstitial lung disease patients to improve morbidity and mortality outcomes; and (2) investigate whether novel therapeutic interventions (e.g. anti-fibrotics, hematopoietic stem cell transplantation) o...

    • Figure 1

      Contemporary studies of systemic sclerosis consistently...

  2. 15 Ιαν 2024 · People who have interstitial lung disease along with systemic sclerosis are much more likely to die from disease complications than people who do not have lung disease. Around 80% to 90% are alive five years after being diagnosed with interstitial lung disease from systemic sclerosis.

  3. 15 Ιουλ 2017 · The 5-year mortality for patients with progressive systemic sclerosis and ILD have a survival of 8290% in 5 years, with ILD or pulmonary hypertension being responsible for 60% of the mortality observed in such cases [5].

  4. 20 Ιαν 2021 · The purpose of this review is to highlight the recent advances in the evaluation and management of patients with pulmonary manifestations of SSc. We also engage in a systematic literature review to assess all the available data on the survival of patients with SSc after lung transplantation.

  5. 15 Ιουν 2024 · When scleroderma affects the heart or lungs, it can cause shortness of breath, decreased exercise tolerance and dizziness. Scleroderma can cause scarring in the lung tissues that may result in increasing shortness of breath over time.

  6. 3 Νοε 2023 · Limited SSc–ILD is characterized by an extent of lung fibrosis <20% on HRCT or indeterminate lung involvement on HRCT and an FVC ≥70% of predicted, whereas extensive disease (which is ...

  7. Pulmonary involvement in systemic sclerosis In scleroderma, the two most common types of direct pulmonary involvement are ILD and PH, which together account for 60% of SSc-related deaths [2].