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  1. 11 Απρ 2024 · For patients with a new focal presentation, the differential diagnoses by region include the following: Upper motor neuron (UMN) bulbar signs: Brainstem lesions including syrinx, mass,...

  2. 28 Δεκ 2022 · Amyotrophic lateral sclerosis typically is diagnosed in middle age. There is a recognized male predilection 1. Clinical presentation. Both upper and lower motor neurons are affected, with decreased motor strength and wasting of the limb muscles, bulbar muscles, and diaphragm.

  3. 18 Οκτ 2023 · This topic will review the clinical evaluation and laboratory testing needed to support the diagnosis of ALS and other forms of motor neuron disease as well as the differential diagnosis of ALS. Other aspects of ALS are discussed separately.

  4. 25 Οκτ 2019 · Parkinson's disease can be easily delineated from ALS on the clinical presentation (tremor, rigor, and akinesia) and the results of the single-photon emission computed tomography investigations of presynaptic dopamine receptors in the midbrain.

  5. 7 Ιουλ 2020 · Important differential diagnoses. The diagnosis of ALS in patients with a typical disease presentation is relatively straightforward and is based on the recognition of signs of UMN and LMN degeneration, in the presence of a progressively worsening spread of symptoms or signs within a region or to other regions (Fig. 2). However, in patients ...

  6. 3 Φεβ 2021 · The SI can, in early diagnosis of ALS, differentiate ALS from mimic disorders. An essential step in using the Awaji-Shima criteria [ 68 ] is to examine a sufficient number of muscles with a needle electrode.

  7. In this review, different aspects of ALS are discussed, including epidemiology, aetiology, pathogenesis, clinical features, differential diagnosis, investigations, treatment and future prospects.

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