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  1. 15 Ιουν 2024 · Scleroderma is often categorized as limited or diffuse, which refers only to the degree of skin involvement. Both types can involve any of the other vascular or organ symptoms that are part of the disease. Localized scleroderma, also known as morphea, affects only the skin.

    • Morphea

      Causes. The cause of morphea is unknown. It may be caused by...

    • Doctors Departments

      Allergy skin test, Skin biopsy, UV light therapy, Pulsed-dye...

  2. 28 Ιουν 2024 · Diverse fibrosis of the skin and internal organs, vasculopathy, and dysregulated immune system lead to poor and varied prognoses in patients with SSc subtypes. Therefore, this study aimed to develop a personalized tool for predicting the prognosis of patients with SSc.

  3. 15 Ιουν 2024 · Treatment. There is no treatment that can cure or stop the overproduction of collagen that happens in scleroderma. But a variety of treatments can help control symptoms and prevent complications.

  4. 13 Ιουν 2024 · Overall prognosis is variable, depending on the organ(s) involved and the severity. For patients with limited cutaneous involvement, 10-year survival is approximately 75%. However, patients with diffuse involvement have a 10-year survival closer to 55% 5.

  5. 25 Ιουν 2024 · In addition, updated strategies for the first- and advanced-line therapy of sclerosing skin diseases are addressed in detail. Part 1 of this consensus provides clinicians with an overview of the diagnosis and treatment of localized scleroderma (morphea), and systemic sclerosis including overlap syndromes.

  6. 14 Ιουν 2024 · Clinical photograph of a patient with diffuse systemic sclerosis. Orofacial findings highlighted include a taut, mask-like skin with notable resorption at the angle of the mandible

  7. 13 Ιουν 2024 · Scleroderma has the highest case fatality rate of all the autoimmune connective tissue diseases, including systemic lupus erythematosus and rheumatoid arthritis, Hinchliff points out. Lung disease is a leading cause of death in patients with scleroderma.

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