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All types of Charcot-Marie-Tooth disease (CMT) damage the peripheral nerves, leading to muscle weakness and some loss of sensation in the arms, legs, hands, and feet. These symptoms often first appear during adolescence or early adulthood, but can develop later in life, as well.
A small fraction of people with CMT develop “flat feet” (pes planus), presumably because of a different pattern of muscle weakness. During walking, these deformities can cause unusual friction against the toes, heel, and ball of the foot, leading to painful abrasions, blisters, and calluses.
8 Μαρ 2023 · You may also experience loss of sensation and muscle contractions, and difficulty walking. Foot deformities such as hammertoes and high arches also are common. Symptoms usually begin in the feet and legs, but they may eventually affect your hands and arms.
Charcot-Marie-Tooth disease is a hereditary neuropathy in which the muscles of the lower legs become weak and waste away (atrophy). Charcot-Marie-Tooth disease affects nerves that control muscle movement and those that carry sensory information to the brain.
Images. summary. Charcot-Marie-Tooth Disease, also known as peroneal muscular atrophy, is a common autosomal dominant hereditary motor sensory neuropathy, caused by abnormal peripheral myelin protein, that presents with muscles weakness and sensory changes which can lead to cavovarus feet, scoliosis, and claw foot deformities.
8 Οκτ 2021 · In patients with Charcot-Marie-Tooth disease (CMT), distal muscle wasting may be noted in the legs, resulting in the characteristic stork leg or inverted champagne bottle appearance. Bony...
26 Σεπ 2018 · Charcot-Marie Tooth (CMT) disease is a condition that commonly produces a high arched foot. CMT is associated with weakness of the many lower extremity muscles. It is caused by abnormalities in nerve conduction (too much myelin in the nerve sheath).
