Αποτελέσματα Αναζήτησης
23 Οκτ 2016 · Introduction. Pacemaker myocytes in the sinoatrial node of the heart (sinoatrial myocytes, "SAMs") generate spontaneous, rhythmic action potentials (APs) that propagate through the myocardium to initiate each heartbeat.
6 Ιουν 2020 · Primary cell culture is an integral resource that offers a controlled environment for detailed mechanistic studies of cardiac myocyte function. Due to their more durable nature and ease of isolation, neonatal rat atrial and ventricular myocytes have been the common source of such cell cultures 1 .
6 Ιουν 2014 · We will first discuss different methods to assess heart function that may change under different genetic and environmental conditions, as well as with age. Then we will summarize tools and markers for structural features of the heart during development, maintenance and aging.
1 Ιουλ 2022 · Abstract. Cardiac fibroblasts play a critical role in extracellular matrix homeostasis, wound healing, and cardiac interstitial fibrosis: the latter being a pathophysiological response to a chronic increase in afterload.
16 Μαΐ 2022 · Here, we provide a complete morphological description of mammalian heart tube formation based on detailed imaging of a temporally dense collection of mouse embryonic hearts.
The most recognized function of t-tubules is regulation of cardiac EC coupling by concentrating voltage-gated L-type calcium channels (LTCCs) and positioning them in close proximity to calcium sense and release channels, ryanodine receptors (RyRs), at the junctional membrane of sarcoplasmic reticulum (jSR).
11 Μαρ 2021 · Here the authors reveal that in the heart, microtubules spatiotemporally regulate mRNAs and ribosomes to build new sarcomeres, a role which is essential for growth.
