Αποτελέσματα Αναζήτησης
5 ημέρες πριν · Substantial heterogeneity in molecular features, patient prognoses, and therapeutic responses in head and neck squamous cell carcinomas (HNSCC) highlights the urgent need to develop molecular classifications that reliably and accurately reflect tumor behavior and inform personalized therapy.
5 ημέρες πριν · Developing effective treatments for patients with head and neck squamous cell carcinoma (HNSCC) is a significant challenge. Cetuximab, a first-line targeted therapy for HNSCC, exhibits limited efficacy.
4 ημέρες πριν · The study, "Checkpoint blockade-induced CD8+ T cell differentiation in head and neck cancer responders", examines the impact of ICB on the TME. It highlights the heterogeneity and differentiation of CD8+ tumor-infiltrating lymphocytes (TILs), suggesting that understanding these dynamics could improve ICB responses.
2 ημέρες πριν · Head and neck squamous cell carcinoma (HNSCC) is a devastating disease. Despite morbid treatment, 5-year survival rates remain poor (28%-67%) [ 1 ]. There is a significant knowledge gap regarding how the microbiota may impact HNSCC treatment efficacy [ 2 ].
4 ημέρες πριν · Concurrent chemoradiotherapy (CCRT) is the standard treatment for patients with locally advanced squamous cell carcinoma of the head and neck (HNSCC). Pneumonia is a significant complication in these patients.
3 ημέρες πριν · In view of improving biomarkers predicting the efficacy of immunotherapy for head and neck squamous cell carcinoma (R/M HNSCC), this multicenter retrospective study aimed to identify clinical, tumor microenvironmental, and genomic factors that are related to therapeutic response to the anti-PD-1 antibody, nivolumab, in patients with R/M HNSCC.
4 ημέρες πριν · Head and neck cancer (HNC), a prevalent and combative malignancy with a high mortality rate (Johnson et al., 2020). It originates from various primary sites, including the oral cavity, oropharynx, nasopharynx, larynx, hypopharynx, and tongue, with squamous cell carcinoma (SCC) being predominant.
