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4 Ιουλ 2024 · Cognition is also affected in up to 50% of people with ALS, with some individuals progressing to a severe form of dementia known as frontotemporal dementia (FTD) 14.
2 ημέρες πριν · The pathogenic mutation is a hexanucleotide repeat expansion (a series of six nucleotides repeated over and over); people with up to 30 repeats are considered normal, while people with hundreds or thousands of repeats can have familial ALS, frontotemporal dementia, or sometimes sporadic ALS.
6 Ιουλ 2024 · Parkinson's disease and Alzheimer's disease are both neurological conditions caused by neurodegeneration (gradual damage to brain cells). Like other progressive brain diseases, they are associated with a buildup of certain proteins in the brain.
6 ημέρες πριν · Summary: A traumatic brain injury (TBI) can quadruple your risk for developing dementia and increase your chances of developing neurodegenerative diseases such as ALS. In a new study scientists...
2 Ιουλ 2024 · Based on a significantly increased incidence of ALS in a small geographical region from Spain, the aim of this work was to identify novel ALS-related genes in ALS cases with negative genetic testing.
10 Ιουλ 2024 · New 12-month results from the PARADIGM clinical trial (NCT05357950) demonstrated a significant improvement in the rate of decline of Amyotrophic Lateral Sclerosis (ALS) Functional Rating Scale-Revised (ALSFRS-R) scores and survival rates for adults with ALS treated with PrimeC (ciprofloxacin/celecoxib; NeuroSense Therapeutics, Cambridge, MA) ...
9 Ιουλ 2024 · Levels of TDP-43 and tau isoforms in plasma extracellular vesicles (EVs) can discriminate between different molecular subtypes of frontotemporal dementia (FTD), amyotrophic lateral sclerosis (ALS...
