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  1. 1 ημέρα πριν · SARS-CoV-2 demonstrated a broader ability to infect various lung cell types through canonical and noncanonical pathways. The virus also triggered an innate immune response in pulmonary epithelial cells, inducing interferons, cytokines, and chemokines independently of immune system cells. In LOs, viral replication led to mitochondrial apoptosis ...

  2. 2 ημέρες πριν · A total of 217 individuals with confirmed SARS-CoV-2 infection were recruited between January and December 2021.Samples were collected <7 days after symptom onset. Based on available metadata, participants were classified as asymptomatic (n = 62) and symptomatic (n = 155).Cell phenotyping was performed on baseline samples from all 217 individuals and longitudinal samples up to 1 month post ...

  3. 2 ημέρες πριν · Scientists infect miniature lung organoids with the virus responsible for COVID-19, revealing new ways in which the infection spreads and suggesting potential treatments. ... San Diego and their international collaborators have reported that more types of lung cells can be infected by SARS-CoV-2 than previously thought, including those without ...

  4. 1 ημέρα πριν · Importance The COVID-19 pandemic has led to 775 million documented cases and over 7 million deaths worldwide as of March 2024 and is an ongoing health crisis. To limit viral spread within households and in the community, public health officials have recommended self-isolation, self-quarantine of exposed household contacts, and mask use. Yet, risk of household transmission (HHT) may be ...

  5. 8 ώρες πριν · By infecting the cells of the upper respiratory tract, bronchial epithelium, and alveolar type II pneumocytes (ATII), SARS-CoV-2 can trigger the onset of variable clinical manifestations that can range from asymptomatic infection to acute lung injury, severe pneumonia, and death, especially in individuals with certain co-morbidities such as ...

  6. 3 ημέρες πριν · News Release 23-Jul-2024. Mini lungs make major COVID-19 discoveries possible. Scientists infect miniature lung organoids with the virus responsible for COVID-19, revealing new ways in which the ...

  7. 2 ημέρες πριν · Among affected individuals, 47% reported symptoms lasting at least 1 year and 21% described symptoms that often or always limited daily activities. The national survey also found that 27% of patient with SARS-CoV-2 developed long COVID following the Alpha variant infection compared to 13% with the Omicron variant .

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