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Down syndrome (DS, trisomy 21) is the most common survivable aneuploidy. Individuals with DS may experience multiple comorbid health problems including congenital heart defects, endocrine abnormalities, skin and dental problems, seizure disorders, leukemia, dementia, and obesity.
- Another Piece in This Complicated Puzzle
As described previously, seizures in Down syndrome could be...
- Conference Proceedings
A December 2010 meeting, “Down Syndrome: National Conference...
- Expression of The Anthracycline-Metabolizing Enzyme Carbonyl Reductase 1 in Hearts From Donors With Down Syndrome
Introduction. Down syndrome (DS) is the most common genetic...
- Another Piece in This Complicated Puzzle
Compare risks and benefits of common medications used for Down Syndrome. Find the most popular drugs, view ratings and user reviews.
Class Summary. Pain control is essential to quality patient care. It ensures patient comfort and promotes pulmonary toilet, and analgesics have sedating properties that are beneficial for...
4 Μαρ 2022 · People with Down syndrome can be more sensitive to medications and they have an increased risk of poor medication adherence. Use these medication management tips to ensure safe and effective treatment regimens.
Some people with Down syndrome take amino acid supplements or drugs that affect their brain activity. However, many of the recent clinical trials of these treatments were poorly controlled and revealed adverse effects from these treatments.
Results: We identify 23 categories of commonly occurring medical conditions and 24 categories of medications used by adults with Down syndrome. Conclusion: Approximately 75 of older adults with Down syndrome in our sample experience memory loss and dementia. Hypothyroidism, seizures, and skin problems also occur commonly.
Electroconvulsive therapy is considered if pharmacotherapy is ineffective. We treat 'regression' with symptoms of MDD ± psychosis, with an antidepressant and an antipsychotic if needed. Randomized controlled trials of medications for comorbid psychiatric disorders in DS are warranted.
