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26 Απρ 2016 · Less cardiotoxicity is seen with TCH (docetaxel, carboplatin, and trastuzumab) than with AC→TH (doxorubicin and cyclophosphamide→docetaxel and trastuzumab), and TCH is recommended for patients at higher risk for cardiotoxicity.*
This protocol is part of the AC-TH regimen: 4 cycles of AC, followed by 4 cycles of TH and 13 cycles of trastuzumab. Link to Breast adjuvant AC-TH overview; Link to Breast adjuvant AC (DOXOrubicin and CYCLOPHOSPHamide) three weekly; Drug status: Docetaxel is on the PBS general schedule. Trastuzumab is PBS authority
AC (Adriamycin® + Cyclophosphamide) followed by THP (Taxol® + Herceptin® + Pertuzumab) is a Chemotherapy Regimen for Breast Cancer - early stage. How does AC-THP work? Doxorubicin, cyclophosphamide, and paclitaxel are chemotherapy drugs designed to kill or slow the growth of cancer cells.
Key inclusion criteria were pT1–3 and node-positive (pN+) tumours or pT2–3N0 tumours with at least one of the following risk factors: (1) grade II/III; (2) lymphovascular invasion; (3) ≤35 years of age; (4) estrogen receptor (ER) and progesterone receptor (PR) negative.
9 Μαΐ 2024 · The findings, showing comparable DFS and pCR rates between the DTP regimen and the standard AC-taxan/TP treatments, suggest that DTP may offer the advantage of reducing the severe...
31 Ιουλ 2017 · The two most commonly used regimens in the United States are ACTH (doxorubicin, cyclophosphamide, paclitaxel, and trastuzumab) and TCH (docetaxel, carboplatin, and trastuzumab). No clinical...
7 Δεκ 2022 · The following material represents a subset of chemotherapy and immunotherapy regimens that are used for the treatment of patients with breast cancer, both in the adjuvant and neoadjuvant settings.
