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Hypoventilation (also known as respiratory depression) occurs when ventilation is inadequate (hypo meaning "below") to perform needed respiratory gas exchange. [1] By definition it causes an increased concentration of carbon dioxide (hypercapnia) and respiratory acidosis.
11 Ιουλ 2024 · Alveolar hypoventilation, defined as an elevation in PaCO₂ to levels >45 mmHg, can occur with several disorders: obesity hypoventilation syndrome, restrictive thoracic disorders, central sleep apnea syndromes, and COPD.
Central hypoventilation syndrome (CHS) is a sleep-related breathing disorder that causes ineffective breathing, apnea, or respiratory arrest during sleep (and during wakefulness in severe cases). CHS can either be congenital (CCHS) or acquired (ACHS) later in life.
22 Οκτ 2018 · Alveolar hypoventilation is when the alveolar ventilation is insufficient compared to the requirements of the body. It’s defined as when the arterial pCO 2 is increased above the normal 44 mmHg. Primary alveolar hypoventilation is a type of alveolar hypoventilation with no known etiology.
1 Δεκ 2008 · Central alveolar hypoventilation disorders are rare and complex disorders that may involve alterations in mechanisms of ventilatory control and autonomic dysfunction. These disorders may be congenital or acquired and are associated with significant morbidity and mortality.
25 Μαΐ 2017 · Hypoventilation syndromes are characterized by a decrease in minute ventilation resulting in an elevated partial pressure of carbon dioxide (PCO 2) with a relatively normal pH and an elevated bicarbonate level suggesting chronic compensation for respiratory acidosis.
The ventilatory control system normally compensates for this by increasing drive to maintain adequate alveolar ventilation levels, thereby keeping arterial CO2 within its normal range. To reduce work of breathing, a pattern of reduced tidal volume and increased respiratory rate occurs.
