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26 Απρ 2024 · Local anesthetics (LAs) are used to block transmission of impulses in nerve fibers, to reduce or eliminate sensation. LAs may be used for neuraxial analgesia and anesthesia, peripheral nerve blocks, subcutaneous and tissue infiltration, and topical anesthesia.
17 Ιουλ 2019 · Illustrate the relationships between the structure, function and toxicity of local anaesthetic agents. Identify the pharmacological profiles of commonly used local anaesthetics. Local anaesthetic agents suppress action potentials in excitable tissues by blocking voltage-gated Na + channels.
17 Αυγ 2023 · Bupivacaine is a potent local anesthetic with unique characteristics from the amide group of local anesthetics, first discovered in 1957. Local anesthetics are used in regional anesthesia, epidural anesthesia, spinal anesthesia, and local infiltration.
In this review, we describe the development of articaine, explain its mechanism of action, compare its efficacy with that of other commonly used local anesthetics in dental treatment, and summarize the application of articaine in special populations.
17 Αυγ 2023 · Bupivacaine is a potent local anesthetic with unique characteristics from the amide group of local anesthetics. Local anesthetics are used in regional anesthesia, epidural anesthesia, spinal anesthesia, and local infiltration.
Local anesthetics may be classified into groups, including esters (aminobenzoate and benzoic acid subtypes), amides, ethers, and ketones. Contact dermatitis is the most common allergic reaction to local anesthetics.
1 Δεκ 2015 · There are two types of local anesthetics (aminoamides and aminoesters), which are distinguished by their chemical linkage and metabolism. Ester local anesthetics undergo hydrolysis by plasma esterases, whereas amides undergo biotransformation mainly in the liver.
