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21 Οκτ 2024 · IL-11 inhibition offers a promising strategy, with preclinical trials demonstrating its ability to regenerate renal cells, reduce hepatocyte death, and mitigate liver fibrosis. Further research is necessary to fully elucidate the mechanisms of IL-11 inhibition and its therapeutic potential.
17 Ιουλ 2024 · Administration of anti-IL-11 to 75-week-old mice for 25 weeks improves metabolism and muscle function, and reduces ageing biomarkers and frailty across sexes.
20 Οκτ 2024 · We highlight a recent study published in Nature which explored the role of interleukin-11 (IL-11), a pro-inflammatory cytokine, in aging. 1 The study demonstrates how inhibiting IL-11 signaling can positively impact both healthspan and lifespan in mice, suggesting a novel target for antiaging therapies with significant implications for ...
16 Ιουν 2023 · 9MW3811 is a monoclonal antibody designed to target interleukin-11 (IL-11), an immune signaling molecule that’s been implicated in the scar tissue buildup (fibrosis) and inflammation that characterize IPF.
31 Δεκ 2022 · An in-house antibody generation campaign identified a diverse, high affinity set of anti-interleukin-11 (IL-11) monoclonal antibodies (mAbs) to enable successful development of novel,...
Find the IL-11 antibody that fits your needs. Choose from 1 of 18 IL-11 antibodies, which have been validated in experiments with 11 publications and 29 images featured in our data gallery. Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications.
25 Σεπ 2019 · We generated an IL-11-neutralizing antibody that blocks lung fibroblast activation downstream of multiple stimuli and reverses myofibroblast activation. In therapeutic studies, anti-IL-11 treatment diminished lung inflammation and reversed lung fibrosis while inhibiting ERK and SMAD activation in mice.
