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Bioartificial liver (BAL) support systems have a potential effect to provide temporary support to bridge patients with acute liver failure to liver transplantation or spontaneous recovery. In the past decades, several BAL support systems have been conducted in clinical trials, but remained verified.
18 Φεβ 2021 · Liver support therapies can be applied as a bridging-to-transplantation or bridging-to-recovery; however, results of clinical trials are controversial. Our aim was to compare liver support...
15 Νοε 2018 · At the end of the last century, some artificial liver devices began to develop with the aim of being used as supportive therapy until liver transplantation (bridge-to-transplant) or liver regeneration (bridge-to-recovery).
29 Οκτ 2013 · Artificial and bioartificial liver support systems are extracorporeal devices that are intended to supplement standard intensive care in patients with liver failure by supporting the...
12 Νοε 2008 · An anhepatic dog model is used to demonstrate the efficacy of a bioartificial liver assist device capable of replacing the metabolic function of the liver, and might provide hepatic support in patients awaiting transplantation or in fulminant hepatic failure.
1 Σεπ 2014 · The original Hepatix, Inc (Houston, TX), device supported dogs with lethal acetaminophen-induced liver failure until their native livers had recovered, and they were able to survive without further support. 11, 20 The original device also appeared to be effective in supporting 23 patients with ALF. 14, 15 The modified device was tested in 5 ...
Abstract: We have used an anhepatic dog model to demonstrate the efficacy of a bioartificial liver assist device. Six dogs underwent total hepatectomy. Three received only medical care (controls) while the remainder were connected to an extracorporeal liver assist device (ELAD).
