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21 Ιουν 2022 · As of April 2022, forty-four cases of intravenous immunoglobulin-induced aseptic meningitis have been reported in the English-language literature. This review aims to provide a thorough overview of the diagnostic process, pathophysiology, possible preventative measures and adequate treatment of IVIG-induced aseptic meningitis.
I have an immunology patient who has received IVIG for several years. After his last Gammunex infusion, he was hospitalized for 5 days with a diagnosis of aseptic meningitis. I need guidance on how to proceed with his treatments.
15 Μαΐ 2022 · Aseptic meningitis, an uncommon but significant adverse reaction of IVIG therapy, can prove a diagnostic obstacle. As of April 2022, forty-four cases of intravenous immunoglobulin-induced aseptic meningitis have been reported in the English-language literature.
13 Μαΐ 2024 · Abstract. An acute aseptic meningitis has been occasionally observed on intravenous polyclonal human immunoglobulin therapy. Since case reports cannot be employed to draw inferences about the relationships between immunoglobulin therapy and meningitis, we conducted a systematic review and meta-analysis of the literature.
Aseptic meningitis as a side effect from IVIG has significant impact, and no defined treatment. This simple series suggest that inhibition of microtubule formation may protect patients from CSF inflammation triggered by IVIG treatment. Article metrics. View abstract.
Aseptic meningitis has been reported in pediatric patients receiving IVIG therapy 10-15 and this case series describes the occurrence of aseptic meningitis after IVIG for MIS-C in the Overcoming COVID-19 cohort.
Even if the patient develops IVIG-associated aseptic meningitis, IVIG therapy need not be withheld and should be continued at a slow infusion rate, with proper hydration, antihistamines and analgesics, as it is a life-saving drug for GBS.
