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The autoimmune theory of aging, introduced by Roy L. Walford in 1969, asserts that with age, the immune system tends to lose efficiency and experiences widespread dysfunction, evidenced by autoimmunity (immune reactions against one's own body proteins) and a decreased ability to respond to infection and other immune challenges.
1 Μαΐ 2014 · In this chapter, we will review the age-related changes in the immune response and assess the validity of the immune theory of aging (i.e. that these changes in immune response...
1 Ιαν 2022 · The immune system has a major role in the defense of the organism, but many changes occur during life which are considered mostly detrimental for longevity and health due to collateral damage caused by immunopathology. This may be considered the central concept of the immunological theory of aging.
In this chapter, we will review the age-related changes in the immune response and assess the validity of the immune theory of aging (i.e. that these changes in immune response are the primary cause of aging).
22 Οκτ 2023 · The autoimmune theory proposes that the immune system is programmed so that it is no longer able to faultlessly distinguish foreign proteins from the body’s own proteins. If this happens the body’s immune system will attack and destroy its own cells.
1 Ιαν 2022 · In this chapter, immunosenescence, autoimmune diseases, fundamental changes of cellular aging, age-related clinical manifestations, and the epidemiology of autoimmune diseases in elderly individuals will be discussed.
The autoimmune theory proposes that the immune system is programmed so that it is no longer able to faultlessly distinguish foreign proteins from the body’s own proteins. If this happens the body’s immune system will attack and destroy its own cells.
