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8 Νοε 2022 · This highlights the possibility of the gut microbiota as a novel therapeutic target for depression. Accumulating evidence supports the efficacy of various microbiota-target therapeutics in alleviating depression, including dietary interventions, FMT, probiotics, prebiotics, synbiotics, and postbiotics.
22 Ιουλ 2021 · A growing body of evidence supports an important role for alterations in the brain-gut-microbiome axis in the aetiology of depression and other psychiatric disorders.
26 Οκτ 2022 · To advance microbiota-based diagnostics and therapeutics of depression, a comprehensive overview of microbial alterations in depression is presented to identify effector microbial biomarkers. This procedure generated 215 bacterial taxa from humans and 312 from animal models.
22 Ιουλ 2021 · Signs of oral dysbiosis were evident in our depressed cohort with ASVs corresponding to Prevotella nigrescens, a bacterial species previously linked to periodontitis 34 and Th17 immune responses in-vivo 35, demonstrating the most increased abundance in depression.
26 Μαΐ 2024 · Alternative approaches to the treatment of depression are being considered by balancing the microbial composition through dietary modifications and the use of additives, namely probiotics, postbiotics (including vesicles) and prebiotics as psychobiotics, and fecal transplantation.
Growing evidence indicates the community of microorganisms throughout the gastrointestinal tract, (i.e., gut microbiota), is associated with anxiety and depressive disorders. We present the first systematic review of the gut microbiota in anxiety disorders, along with an update in depression.
The studies presented in this paper largely demonstrate encouraging results in the treatment of depression. Limitations include small sample sizes and heterogeneous methodology. The exact mechanism by which the gut microbiota causes or alters neuropsychiatric disease states is not fully understood.
