Αποτελέσματα Αναζήτησης
28 Ιαν 2021 · The purpose of this guideline is to develop recommendations concerning the optimal use of systemic neoadjuvant therapy, including chemotherapy, endocrine therapy, and targeted therapy for patients with invasive breast cancer.
- Preoperative Chemotherapy
Preoperative therapy, initially used only for locally...
- Impact
The Immediate Preoperative Anastrozole, Tamoxifen, or...
- Gbg 69–GeparSepto
Taxanes (paclitaxel and docetaxel) are standard-of-care...
- Primary
In the Gepartrio (German Breast Group) trial, therapy is...
- Preoperative Chemotherapy
While searching for new bioactive compounds, it has been observed that organic molecules with benzoic acid (BA) moiety possess significant anticancer potential. Several works of literature reported the use of BA from natural or synthetic sources to synthesize bioactive chemicals.
29 Μαΐ 2023 · During the process of looking for new chemical entities, it was found that certain compounds with a basic nucleus of benzoic acid (BA) exhibit a remarkable anticancer potential.
29 Ιουλ 2020 · The aim of this review is to provide an overview on diverse anticancer activities of 2-substituted benzimidazole derivatives. This review provides a correlation between the various mechanisms of action of benzimidazoles as anticancer and the substitution pattern around the nucleus.
1 Δεκ 2016 · In conclusion, the review summarized: (a) key structural features of phenolic acids required for exhibiting anti-cancer activity; (b) the recently published data highlighting the beneficial effects of biotransformation of phenolic acids by gut microbiota; (c) the mechanisms of action(s) of phenolic acids leading to the inhibition of cancer cell ...
10 Ιουν 2021 · Benzoic Acid. The estrogen receptor α (ERα) is identified as an effective target for the treatment of ERα+ breast cancer; thus, discovery of novel selective estrogen receptor degraders (SERDs) are developed as an effective method to overcome the resistance of breast cancer. Herein, the hot-spot residues for prote ….
20 Μαΐ 2024 · In 2020, ASCO published a guideline on the selection of optimal adjuvant chemotherapy and targeted therapy for breast cancer. 1 This is a rapid recommendation update of that guideline that addresses, in turn, the adjuvant use of the cyclin-dependent kinase 4 and 6 (CDK4/6) inhibitors abemaciclib and ribociclib in patients with stage II and III ...
