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15 Ιουν 2021 · Medications like selective serotonin reuptake inhibitors (SSRIs) and clomipramine can improve chemical signals within the brain to reduce OCD symptoms. Medication-free treatment, such as cognitive-behavioral therapy, is important in managing OCD and can be used in combination with medications.
It is generally recommended that OCD be treated with a higher dose of SSRI than that used in depression . A meta-analysis of fixed-dose comparison studies have found a greater efficacy with higher doses of SSRI (60-80 mg fluoxetine equivalent) compared to medium (40-50 mg fluoxetine equivalent) and low doses (20-30 mg fluoxetine equivalent) [ 19 ].
14 Απρ 2022 · Some of the most common antidepressants are selective serotonin reuptake inhibitors (SSRIs). Some medicines work well with some people but not with others. Antidepressants and SSRIs may...
Though traditionally used to treat depression, research has shown SSRIs to be the most effective medications for OCD, as well. Their positive effects can often be felt within two weeks of starting treatment.
22 Σεπ 2021 · Serotonin reuptake inhibitors (SRIs), including selective serotonin reuptake inhibitors (SSRIs) and tricyclic antidepressants, such as clomipramine, are the most common choices for the pharmacological treatment of OCD. Optimizing their use is pivotal in guiding clinical practice of OCD.
Based on all 17 studies, SSRIs as a group were more effective than placebo in reducing the symptoms of OCD between 6 and 13 weeks post‐treatment, measured using the Yale‐Brown Obsessive Compulsive Scale (YBOCS) (WMD ‐3.21, 95% CI ‐3.84 to ‐2.57). The WMD for individual SSRI drugs were similar and not statistically different.
The types of medication that research has shown to be most effective for OCD are a type of drug called a Serotonin Reuptake Inhibitor (SRI), which are traditionally used as an antidepressants, but also help to address OCD symptoms.
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