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  1. 1 Νοε 2015 · This article will explore several common theories about why and how we age. By understanding current aging theories, clinicians can follow advances in aging research and intelligently address patient questions about life extension therapies and strategies to slow aging.

  2. 20 Ιουλ 2022 · Abstract. Having made substantial progress understanding molecules, cells, genes and pathways, aging biology research is now moving toward integration of these parts, attempting to understand...

  3. Modern biological theories of aging in humans fall into two main categories: programmed and damage or error theories. The programmed theories imply that aging follows a biological timetable, perhaps a continuation of the one that regulates childhood growth and development.

  4. 22 Αυγ 2020 · Many theories currently trying to explain aging processes and many biomarkers are identified to measure aging and its evolutionary stages. Theories and biomarkers are not studied to extend life span but to guide therapeutic choices and optimize patient management and personalization of care.

  5. 1 Νοε 2015 · Here, we review known biological theories of aging and how ROS mechanistically control senescence and the aging process. We also describe the redox-regulated signaling networks controlling the SASP and its important role in driving age-related diseases.

  6. 1 Ιαν 2022 · The two radically different schools of aging theories, according to which aging is viewed either as a species-specific genetically defined program or as a sequence of stochastic events, should first be attributed to molecular biological theories of aging (Schneider, Gudladt, & Gerold, 1987).

  7. This review critically examines the role of aging in the progressive decline of the mechanobiology occurring in cells, and establish mechanistic frameworks to understand the mechanobiological impacts of aging on disease progression and develop new strategies to halt and reverse the aging process.