Αποτελέσματα Αναζήτησης
6 Ιαν 2023 · Blood tests. The two key tests to detect iron overload are: Serum transferrin saturation. This test measures the amount of iron bound to the protein transferrin that carries iron in your blood. Transferrin saturation values greater than 45% are considered too high. Serum ferritin. This test measures the amount of iron stored in your liver.
The combination of low iron, high TIBC and/or transferrin and low saturation indicates iron deficiency. Without all of these findings together, iron deficiency is unproven. 2 Low ferritin supports the diagnosis of iron deficiency.
A TIBC (total iron-binding capacity) test is a blood test that measures your blood’s ability (capacity) to attach (bind) to iron and carry it throughout your body. Healthcare providers use it to help diagnose iron-deficiency anemia and other iron metabolism conditions.
The normal range is 15 – 300 µg/dL. The sensitivity and specificity of the test vary depending on cut-off levels used to define iron deficiency; at a cut-off level of 15µg/L, the test is highly specific for iron deficiency, but lacks sensitivity. At a cur-off level of 100µg/L, the sensitivity increases to 94%, at the expense of specificity (71%).
Serum iron studies are useful in the evaluation of disorders of iron metabolism, particularly iron deficiency and iron excess. Iron studies are best performed when the patient is fasting in the morning and has abstained from medications that may influence iron balance.
A total iron binding capacity value above 450 mcg/dL usually means that there’s a low level of iron in your blood. Elevated TIBC levels are often a sign of the body's response to low iron availability and can indicate various underlying conditions, primarily iron deficiency anemia.
What are these tests? The serum iron test measures the amount of iron in your blood. The total iron-binding capacity (TIBC) test looks at how well the iron moves through your body. Iron is an important mineral that your body needs to stay healthy. Your body uses iron to make hemoglobin.
