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  1. www.cancer.gov › about-cancer › causes-preventionBRCA Gene Changes: Cancer Risk and Genetic Testing

    BRCA1 (BReast CAncer gene 1) and BRCA2 (BReast CAncer gene 2) are genes that produce proteins that help repair damaged DNA. Everyone has two copies of each of these genes—one copy inherited from each parent.

    • Risk Factors

      For example, the finding could be a result of chance, or the...

  2. www.macmillan.org.uk › worried-about-cancer › causes-and-risk-factorsBRCA gene - Macmillan Cancer Support

    BRCA1 and BRCA2 gene variants may cause a: higher-than-average risk of ovarian cancer; slightly higher-than-average risk of pancreatic cancer. And BRCA2 gene variants may also cause a higher-than-average risk of: prostate cancer; breast cancer in men and people assigned male at birth.

  3. www.komen.org › breast-cancer › risk-factorBRCA Gene Mutations - Women | Susan G. Komen®

    Women with a BRCA1 or BRCA2 (BRCA1/2) inherited gene mutation may be called BRCA1/2 carriers. Most risk factors for breast cancer in women likely impact risk the same way for women who are BRCA1/2 carriers and women who are non-carriers.

  4. www.hopkinsmedicine.org › health › conditions-and-diseasesInherited Cancer Risk: BRCA Mutation - Johns Hopkins Medicine

    Inheriting damaged copies of the BRCA1 or BRCA2 genes can increase the risk for breast cancer and ovarian cancer in women and the risk for breast and prostate cancer in men, as well as other cancers. Here is what you need to know about genetic factors in breast cancer, who may be at risk and how people with BRCA mutations can work with their ...

  5. www.ncbi.nlm.nih.gov › books › NBK470239BRCA1 and BRCA2 Mutations - StatPearls - NCBI Bookshelf

    23 Ιουλ 2023 · Breast cancer genes BRCA1 and BRCA2 are tumor suppressor genes whose mutations significantly increase the likelihood of developing particular types of epithelial malignancies, namely breast and ovarian cancer.

  6. www.genomicseducation.hee.nhs.uk › genotes › knowledge-hubBRCA1 and BRCA2 — Knowledge Hub - GeNotes

    BRCA1 and BRCA2 are genes involved in DNA repair. Constitutional (germline) pathogenic variants in these genes are associated with hereditary breast and ovarian cancer, as well as other cancers.

  7. community.macmillan.org.uk › cfs-file › __keyA beginner’sguide to BRCA1 and BRCA2 - Macmillan Cancer Support

    faulty genes are the underlying cause for about 5–10% (5 to 10 in 100) of breast cancers. There are two genes that, if mutated, greatly increase an individual’s chance of developing breast and ovarian cancer. These are known as the BRCA1 (Breast Cancer 1) and BRCA2 (Breast Cancer 2) genes. These two genes account for approximately

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