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25 Σεπ 2006 · Increased levels in dogs typically indicate liver or bone disease, or that the dog is taking prednisone. Liver and bone disease are the most common causes for increased values in cats. ALT is an enzyme produced in the liver, and values found in the bloodstream increase with a diseased or damaged liver.
ALP (alkaline phosphatase) elevations may indicate liver damage, Cushing's disease, active bone growth in young pets, or arthritis or bone degeneration in older pets. ALT (alanine aminotransferase) is a sensitive indicator of active liver damage but does not indicate the cause.
30 Νοε 2023 · To help you sort through your dog’s liver enzyme elevations, integrative veterinarian Dr. Julie Buzby explains the four main liver enzymes (ALT, AST, ALP, and GGT) and discusses the causes, diagnosis, treatment, and prognosis for high liver enzymes in dogs.
Increased liver enzyme activities are common results in small animal practice and can suggest patterns of liver disease, including hepatocellular damage, cholestasis, or both. Liver enzymes, especially ALP, are not specific for primary liver disease.
When levels are increased in the blood, it means that the enzymes have leaked out of the liver cells due to cell damage. AST is found in muscle cells as well as liver cells, so an elevation in AST without a similar elevation in ALT may indicate muscle damage rather than liver damage.
23 Απρ 2021 · When ALT levels in the blood are high, it tells us that liver cells are breaking down more quickly than usual. What it doesn’t tell us, is why. The liver might be perfectly healthy, but the metabolism too fast: this is common in Hyperthyroid cats.
Although some dogs may show no signs, typical signs include loss of appetite, excessive thirst and urination, fever, vomiting, jaundice, and an enlarged liver. Affected animals may collapse and have pale mucous membranes due to rupture of the liver and subsequent internal bleeding.
