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  1. 25 Ιουν 2021 · The CodeBreaK 100 trial, funded by Amgen and NCI, is testing sotorasib (previously called AMG510) as a treatment for people with solid tumors that have KRAS G12C. The mutation, a hallmark of damage from cigarette smoke, is most common in lung cancer.

  2. 22 Μαρ 2024 · Thousands of patients in England with suspected lung cancer are being offered a blood test which can show if they can get early access to targeted therapies. The test looks for genetic...

  3. 11 Αυγ 2023 · Recently, the phase 3 multicenter CodeBreak 200 clinical trial (NCT04303780) of a type of combined treatment using sotorasib and docetaxel has been used for patients with locally progressive and unresectable or metastatic NSCLC with KRAS G12C mutations [37, 38, 39, 40].

  4. 2 Σεπ 2022 · The use of positron emission tomography (PET) could increase the proportion of patients in whom lung cancer is diagnosed in the early stages and thereby reduce lung cancer mortality. The problem is how to increase the number of patients who undergo PET.

  5. Key Points. Non-small cell lung cancer is a type of cancer that forms in the tissues of the lung. There are several types of non-small cell lung cancer. Smoking is the major risk factor for non-small cell lung cancer. Signs and symptoms of non-small cell lung cancer include coughing and shortness of breath.

  6. 2 ημέρες πριν · Your cancer cells will be carefully tested in a lab to find out what type of lung cancer you have. The results can help determine the likely outcome of your cancer, called the prognosis, and guide your treatment.

  7. 14 Ιουλ 2021 · Biomarker testing. The management of advanced lung cancer was anchored in chemotherapy and based on histology. However, during the past decade, the discovery of predictive biomarkers has created new therapeutic opportunities with targeted therapy and immunotherapy (figure 2).

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