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Intrahepatic cholestasis of pregnancy (ICP) is a liver disease specific to pregnancy, characterised by pruritus and increased total serum bile acids (TSBA), with an Australian incidence of 0.6-0.7%. The pathophysiology involves genetic, hormonal and environmental factors.
Introduction. Intrahepatic cholestasis of pregnancy (ICP) occurs in the second and third trimesters of pregnancy and is charac-terized by pruritus and elevated serum bile acid levels.
Intrahepatic cholestasis of pregnancy (ICP) is the most com-mon liver disease specific to pregnancy. The cardinal symptom of pruritus and a concomitant elevated level of bile acids in the serum and/or alanine aminotransferase (ALT) are suggestive for the diagnosis. Overall, the maternal prognosis is good.
30 Ιουλ 2024 · The perinatal sequelae of intrahepatic cholestasis of pregnancy includes increased risks of preeclampsia, gestational diabetes, preterm birth, neonatal respiratory distress, and neonatal intensive care unit admission (moderate).
11 Ιουλ 2023 · Intrahepatic cholestasis of pregnancy (ICP) is a pregnancy liver disease, characterised by pruritus and increased total serum bile acids (TSBA), Australian incidence 0.6–0.7%. ICP is diagnosed by non-fasting TSBA ≥19 μmol/L in a pregnant woman with pruritus without rash without a known pre-existing liver disorder.
10 Σεπ 2020 · Outline how to diagnose intrahepatic cholestasis of pregnancy. Describe the treatment of intrahepatic cholestasis of pregnancy. Explain interprofessional team strategies for improving care coordination and communication to advance the detection and management of intrahepatic cholestasis of pregnancy and improve outcomes.
9 Αυγ 2022 · This guideline summarises the evidence regarding the diagnosis, and the maternal and fetal risks of intrahepatic cholestasis of pregnancy (ICP), previously called obstetric cholestasis. It provides guidance regarding the different care options available.
