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Furthermore, a very substantial number of dogs and cats with PLE do not have vomiting or diarrhea. Some only have ascites, and some are found fortuitously on routine blood work. This may be especially true of dogs with primary intestinal lymphangiectasia.
1 Μαΐ 2011 · A substantial number of dogs and cats with PLE do not have vomiting or diarrhea, just like a substantial number of dogs and cats with severe hepatic disease do not have an increased ALT or SAP. This may be especially true of dogs with primary intestinal lymphangiectasia.
Severe hypoalbuminemia (i.e., < 2 gm/dl) in an animal with diarrhea suggests a protein-losing enteropathy (PLE); however, diarrhea (even when severe) in no way is sufficient to eliminate hepatic disease as the cause of the hypoalbuminemia.
The causes of chronic diarrhea in dogs are multiple, multiple factors are involved, and the prevalence of different diseases can vary depending on the geographical location. Some diseases can generally be ruled out using relatively simple exams (e.g., intestinal parasites).
When hypoproteinemia is severe, fluid may leak from the circulatory system in to the abdomen, chest, or out of the tiny blood vessels in the limbs, causing swelling of the legs. What breeds most commonly get PLE?
What is protein-losing enteropathy? Protein-losing enteropathy (PLE) is a fancy way of saying that excessive protein is lost from the gastrointestinal tract. Normally, protein that leaks into the intestines is digested into amino acids; these are then reabsorbed and made into protein again.
1 Απρ 2015 · Protein-losing enteropathy (PLE) is defined as the loss of protein from the intestines due to intestinal disease. Often, this results in a decreased serum albumin concentration (hypoalbuminemia), sometimes this is accompanied by a decreased serum globulin concentration (hypoglobulinemia).