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10 Απρ 2017 · Therapeutic gene editing can be administered through two basic strategies: (1) direct in vivo delivery of a gene-editing nuclease and (2) delivery of cells engineered ex vivo to contain a...
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17 Αυγ 2021 · Over the years biological therapy evolved from using stem cells and viral vectors to RNA therapy and testing different genome editing tools as promising gene therapy agents.
30 Απρ 2024 · The development of new PE variants holds significant promise for improving therapeutic gene editing by increasing editing efficiency, expanding targeting range, reducing off-target effects, multiplexing editing capability, enhancing delivery systems, and reducing immunogenicity.
11 Ιουν 2024 · View Full Text View PDF Application of the CRISPR/Cas9-based gene editing technique in basic research, diagnosis, and therapy of cancer
7 Ιουν 2019 · The enormous knowledge and ongoing research have now been able to demonstrate methodologies that can alter DNA coding. The techniques used to edit or change the genome evolved from the earlier attempts like nuclease technologies, homing endonucleases, and certain chemical methods.
15 Μαΐ 2018 · Here, we will present a brief history of gene-editing tools and describe the wide range of CRISPR-based genome-targeting tools. We will conclude with future directions and the broader impact of CRISPR technologies.
Therefore, gene editing can be allowed if it is only used to solve human medical and public health problems. Keywords: gene-editing, public health, medical ethics, bioethics
