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  1. 2 Φεβ 2024 · Pseudotumors and high-grade aseptic lymphocyte-dominated vasculitis-associated lesions around total knee replacements identified at aseptic revision surgery: findings of a large-scale histologic review.

  2. 15 Ιουλ 2021 · The incidence of raised cobalt and chromium levels after total knee replacement (TKR) is relatively unknown but it does exist in the presence of loose knee implants and further research is required. A revision of TKR was required for the management of the case.

  3. 1 Μαρ 2022 · While quantitative data on levels of cobalt exposure were not available in most studies, especially OC studies, prior research has suggested that cobalt exposure in arthroplasty patients is low: below 1 μg/L in patients with metal-on-polymer knee implants and ranging from 0.3 to 3.4 μg/L in patients with metal-on-metal hip arthroplasties ...

  4. 8 Νοε 2023 · Cobalt was widely used for hip and knee joint replacements until cases of heavy metal poisoning appeared. Now, researchers from the University of Connecticut School of Medicine and Carnegie Mellon report a way to protect people with these implants from cobalt toxicity.

  5. 9 Σεπ 2024 · Aseptic loosening is a feared and not yet fully-understood complication of total knee arthroplasty (TKA). Hypersensitivity reactions may be the underlying cause within some susceptible...

  6. Systemic cobalt (Co) and chromium (Cr) concentrations may be elevated in patients with metal joint replacement prostheses. ... Cr 3+ concentrations, and has the potential to serve as early markers of metal toxicity. Finally, our study provides a molecular basis for the improved clinical outcomes for hydroxyapatite-coated prostheses that elicit ...

  7. 19 Αυγ 2021 · Most patients presenting to our clinic with cobalt-chrome hip, knee, or shoulder implantations were cobalturic (ie, cobalt levels in urine of 1 ppb or above) and had cobalt levels in urine or blood in excess of levels associated with encephalopathy.

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