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3.2.U3 Eukaryote chromosomes are linear DNA molecules associated with histone proteins. Describe the structure of eukaryotic DNA and associated histone proteins during interphase (chromatin). Explain why chromatin DNA in interphase is said to look like “beads on a string.”
In contrast, the X and Y chromosome synapse only in the short homologous pseudoautosomal regions, and form the so-called XY body. 1 In this specialized chromatin area, transcription is shut down by a mechanism named meiotic sex chromosome inactivation (MSCI) (reviewed by Refs. 2 and 3). The sex chromosomes remain silent throughout the rest of ...
Stern observed several X-linked phenotypes that were associated with a structurally unusual and dissimilar X chromosome pair in which one X was missing a small terminal segment, and the other X was fused to a piece of the Y chromosome.
10 Σεπ 2019 · Chromosome axes play a central role in meiotic chromosome dynamics: The axis assembles in early meiotic prophase (leptotene/zygotene) and is required to initiate meiotic recombination and homolog recognition (2, 3).
23 Απρ 2024 · In meiotic cells, chromosomes are organized as chromatin loop arrays anchored to a protein axis. This organization is essential to regulate meiotic recombination, from DNA double-strand break (DSB) formation to their repair.
23 Μαρ 2006 · Two types of cytological studies suggest that axis-localized protein components occur in multiple horizontal “layers,” with a “supra-axial meshwork” present above the ultrastructurally defined axis.
27 Μαΐ 2020 · Early pachynema was defined as complete autosomal synapsis, whereas the X and Y chromosomes could display various configuration: i) unsynapsed, with thickened PAR axes; ii) engaged in PAR...
