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Depression is one of the leading causes of disability, and, if left unmanaged, it can increase the risk for suicide. The evidence base on the determinants of depression is fragmented, which makes the interpretation of the results across studies difficult.
- Genetic and epigenetic factors associated with depression: An updated ...
Increasing evidence indicates that epigenetic modification...
- Genetic and epigenetic factors associated with depression: An updated ...
Increasing evidence indicates that epigenetic modification is critical in the biological mechanisms of depression, and DNA methylation has been considered a potential link among the environment and depression.
30 Νοε 2021 · While depression affects 300 million people worldwide and is one of the most significant contributors to suicide, the mechanisms behind its onset remain unclear.
20 Ιουλ 2018 · Evidence has suggested that depression could be associated with excess all-cause mortality across different settings and populations, although the causality of these associations remains unclear. We conducted an umbrella review of systematic reviews and meta-analyses of observational studies.
10 Μαΐ 2023 · Various biological and environmental factors across the lifespan increase the vulnerability of key networks to disequilibrium, with potentially modifiable behavioral and social factors...
24 Ιουλ 2024 · Autopsy studies can yield valuable and detailed information on pathological ailments or underreported conditions. This study aimed to compare autopsy-confirmed causes of death (CoD) between individuals diagnosed with major depressive disorder (MDD) and matched controls.
10 Δεκ 2021 · The findings showed that there are a plethora of risk and protective factors (relating to biological, psychological, and social determinants) that are related to depression; these determinants are interlinked and influence depression outcomes through a web of causation.
