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5 Οκτ 2024 · Identify the pathophysiological mechanisms underlying type 1 diabetes, including the role of autoimmune processes and genetic factors, to better inform diagnosis and treatment strategies. Implement the latest advancements in diabetes technology to optimize glycemic control.
6 Ιουν 2018 · Knowledge of type 1 diabetes has rapidly increased over the past 25 years, resulting in a broad understanding about many aspects of the disease, including its genetics, epidemiology, immune and β-cell phenotypes, and disease burden.
5 Οκτ 2024 · Type 1 diabetes mellitus (T1DM) is an autoimmune disease that leads to the destruction of insulin-producing pancreatic beta cells. Insulin is an essential anabolic hormone that exerts multiple effects on glucose, lipid, protein, mineral metabolism, and growth.
28 Ιουν 2019 · This chapter reviews the etiopathogenesis of type 1 diabetes, which includes genetic (such as a strong association with HLA haplotypes, genetic linkage with immune system genes), immunological (such as specificity for beta cells and the presence of antigen-specific T...
7 Φεβ 2023 · Classical Type 1 Diabetes Mellitus Pathoetiology. T1DM arises from the dysregulation of pancreatic β-cell insulin production and insulin effects. Pancreatic β-cell function and insulin release are intimately linked to variations in blood glucose.
3 Μαρ 2023 · Type 1 diabetes mellitus (T1DM) is an autoimmune disease that leads to the destruction of insulin-producing pancreatic beta cells. Insulin is an essential anabolic hormone that exerts multiple effects on glucose, lipid, protein, mineral metabolism, and growth.
16 Απρ 2022 · Type 1 diabetes (T1D) is an autoimmune disease characterized by the T-cell-mediated destruction of insulin-producing β-cells in pancreatic islets. It generally occurs in genetically susceptible individuals, and genetics plays a major role in the development of islet autoimmunity.