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  1. Parkinson disease is the second most common neurodegenerative disorder after Alzheimer disease. 1 Parkinson disease typically develops between the ages of 55 and 65 years and occurs in 1%–2% of people over the age of 60 years, rising to 3.5% at age 85–89 years. 2–4 About 0.3% of the general population is affected, and the prevalence is higher am...

  2. Currently, there isn't a specific test to diagnose Parkinson's disease. A diagnosis is made by a doctor trained in nervous system conditions, known as a neurologist. A diagnosis of Parkinson's is based on your medical history, a review of your symptoms, and a neurological and physical exam.

  3. Parkinson’s disease is traditionally defined, pathologically, by the finding of Lewy bodies and degeneration of catecholaminergic neurones at post-mortem. Using a pathological definition of Parkinson’s disease is problematic for a number of reasons: A pathological diagnosis is not practical in life.

  4. The standard diagnosis of Parkinson’s disease right now is clinical, explain experts at the Johns Hopkins Parkinson’s Disease and Movement Disorders Center. That means there’s no test, such as a blood test, that can give a conclusive result.

  5. Summary. Parkinson's disease is a recognisable clinical syndrome with a range of causes and clinical presentations. Parkinson's disease represents a fast-growing neurodegenerative condition; the rising prevalence worldwide resembles the many characteristics typically observed during a pandemic, except for an infectious cause.

  6. This guideline covers diagnosing and managing Parkinson’s disease in people aged 18 and over. It aims to improve care from the time of diagnosis, including monitoring and managing symptoms, providing information and support, and palliative care.

  7. Symptoms start slowly. The first symptom may be a barely noticeable tremor in just one hand or sometimes a foot or the jaw. Tremor is common in Parkinson's disease. But the disorder also may cause stiffness, slowing of movement and trouble with balance that raises the risk of falls.

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