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The structure of DNA A. Important features of the DNA structure: 1. Right-handed double helix 2. The helices are antiparallel 3. Each helix has a series of nucleotides held together with phosphodiester bonds between the OH groups in two adjacent sugar residues. 4.
Approaches to DNA Sequencing • Chemical degradation of DNA – Maxam-Gilbert – obsolete • Sequencing by synthesis (“SBS”) – uses DNA polymerase in a primer extension reaction – most common approach – Sanger developed it (“Sanger sequencing”) – Illumina, Pacific Biosciences, Ion Torrent, 454 • Ligation-based
27 Οκτ 2010 · Overview. Recall the central dogma of biology: DNA (genetic information in genes) RNA (copies of genes) proteins (functional molecules) DNA structure. One monomer unit = deoxyribonucleic acid. composed of a base, a sugar (deoxyribose), and a phosphate. directionality along the backbone 5’ (phosphate) to 3’ (OH) . Double-strand pairing:
Introduction. Cell-Chromosome-DNA. What’s So Special About DNA? DNA is one of the most boring macromolecules imaginable - its made of only four building blocks and has a perfectly monotonous structure. Worse yet, DNA just sits there - it doesn’t catalyze reactions or build the cell or organism. So, what’s. so. good. about. DNA?
21 Απρ 2015 · The proposal of a double-helical structure for DNA over 60 years ago provided an eminently satisfying explanation for the heritability of genetic information. But why is DNA, and not RNA, now...
how the structure of DNA, with its base-paired strands, (1) holds the genetic information that determines how organisms are built, and (2) is accurately copied to make it possible for genetic information to be inherited when cells
A DNA molecule consists of two long polynucleotide chains composed of four types of nucleotide subunits. Each of these chains is known as a DNA chain, or a DNA strand. Hydrogen bonds between the base portions of the nucleotides hold the two chains together .
