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IL-3 termed multi colony-stimulating-factor (multi-CSF) or mast cell growth factor (MCGF) is a haematopoietic growth factor which stimulates the formation of colonies for erythroid, megakaryocytic, granulocytic and monocytic lineages.
- Mast Cell: A Multi-Functional Master Cell - PMC - PubMed Central (PMC)
When mast cells are stimulated through TLF-7, they release...
- Mast Cells and Interleukins - PMC - PubMed Central (PMC)
In mast cells, IL-33 is a potent inducer of proinflammatory...
- The Multifaceted Roles of Mast Cells in Immune Homeostasis, Infections ...
In this review, we comprehensively discuss the research into...
- Cultured human intestinal mast cells express functional IL-3 ... - PubMed
In the present study, we found expression of IL-3 receptors...
- Mast Cell: A Multi-Functional Master Cell - PMC - PubMed Central (PMC)
When mast cells are stimulated through TLF-7, they release IL-1 and TNFα, which causes dendritic cells to move from their location in the skin and go to local lymph nodes and activate cytotoxic T cells.
In mast cells, IL-33 is a potent inducer of proinflammatory cytokines and chemokines, including IL-5, IL-13, CXCL8, and CCL2, and it is produced by mast cells and regulates IgE-dependent inflammation .
8 Δεκ 2023 · We found that astrocytes and CNS infiltrating CD44 hi CD4 + T cells produce IL-3 during EAE and cell-specific deletion of IL-3 from either source abrogates disease and neuroinflammation.
In this review, we comprehensively discuss the research into roles of MCs in immune homeostasis as well as their multiple roles in the host defense against pathogens, whereby MCs act as sensors and effectors of responses, as controllers of infection and modulators of local inflammation.
27 Ιαν 2021 · We show that IL‐3 is a main factor to stabilize the expression of ICOS‐L on mast cells. Besides that, IL‐3 potentiated the IL‐33‐induced IL‐6 response.
In the present study, we found expression of IL-3 receptors (IL-3R) in freshly isolated human intestinal mast cells by reverse transcriptase (RT)-PCR and in mast cells cultured with stem cell factor (SCF) using RT-PCR and flow cytometry.
