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  1. Low vitamin B2 can lead to mitochondrial dysfunction and may have an effect on migraine pathogenesis. The aim of the present study was to carry out a review of existing evidence regarding the effects of riboflavin (vitamin B2) supplementation on migraine prophylaxis in adults and children.

  2. The mechanism of Vitamin B2 may positively contribute to migraine. This systematic review and meta-analysis aimed to evaluate the impact of Vitamin B2 supplementation on the days, duration, frequency, and pain score of the migraine attack.

  3. 25 Ιαν 2021 · Adults need between 1.1 and 1.3 mg of riboflavin per day, although doses used for migraine prevention are much higher. The Science: Riboflavin and Migraine. Riboflavin is an important part of two major coenzymes within your body.

  4. 18 Ιαν 2016 · The results indicated that supplementation with vitamin B 2 in adults can play a positive role in reducing the frequency and duration of migraine attacks with no serious side effects.

  5. 15 Φεβ 2019 · Résumé: Des vitamines et des minéraux pour traiter de façon préventive la migraine : une revue systématique et une méta-analyse.

  6. 29 Μαρ 2021 · A pooled analysis of available randomized controlled clinical trials demonstrated that Vitamin B2 400 mg/day for three months supplementation had significant effect on days, duration, frequency, and pain score of migraine attacks.

  7. 29 Μαρ 2021 · Vitamin B2 supplementation significantly decreased migraine days (p = .005, I² = 89%), duration (p = .003, I² = 0), frequency (p = .001, I² = 65%), and pain score (p = .015, I² = 84%).

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