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15 Φεβ 2024 · These findings are often associated with various conditions, including Infectious Mononucleosis (IM) due to Epstein-Barr virus (EBV) infection, as well as other infectious and non-infectious causes. Downey type1 cells are smaller in size, have indented to lobulated nucleus and cytoplasmic granules.
- Reactive lymphocyte - American Society of Hematology
These cells are also called Downey type II cells. They can...
- Infectious mononucleosis - American Society of Hematology
The variant lymphocyte in the centre has a classical so...
- Reactive lymphocyte - American Society of Hematology
1 Μαρ 2016 · These cells are also called Downey type II cells. They can be seen in a variety of conditions, but are often increased in infectious mononucleosis due to EBV infection. Download Image
Clinical Picture. Infectious mononucleosis diagnosed by Downey cells: sometimes the old ways are better. Henry M Feder Jr, William N Rezuke. An 18-year-old woman visited her physician because she had a fever, a sore throat, and painful swellings in her neck for the past 5 days.
18 Ιαν 2020 · In 1923, McKinlay and Downey published a description of three types of reactive or atypical lymphocytes, which they called Downey cells. The presence of many of these cells became the standard laboratory test for infectious mononucleosis.
These atypical lymphocytes, also known as Downey cells (Downey 1923), are actually activated CD8 T lymphocytes, most of which are responding to EBV-infected cells. Infectious mononucleosis is medically important because of the severity and duration of the acute illness and also because of its long-term consequences especially the development of ...
14 Σεπ 2017 · The variant lymphocyte in the centre has a classical so called “Ballerina skirt” appearance with scalloped margins and indentations by the surrounding red blood cells. The cytoplasm is vacuolated. Further testing demonstrated positive monospot test confirming Infectious mononucleosis.
Infectious mononucleosis is a clinical entity characterized by pharyngitis, cervical lymph node enlargement, fatigue and fever, which results most often from a primary Epstein–Barr virus (EBV) infection.
