Αποτελέσματα Αναζήτησης
1 Νοε 2022 · Following 1-3 hours preincubation with citicoline, peak stimulations of 20-25% (p < 0.001) and 50-55% (p < 0.001) are seen for acetylcholinesterase and Na + /K +-ATPase respectively, while no significant effects are seen on Mg ++-ATPase.
13 Νοε 2001 · Our studies indicate that citicoline does not provide neuroprotection if the onset of treatment is delayed by 3 hours. Another factor is the percentage of citicoline that is incorporated into the brain.
28 Ιουλ 2012 · The primary objective of this study was to assess the effects of citicoline compared with placebo on the recovery of patients with moderate-to-severe acute ischaemic stroke at 3 months, after having received 2000 mg daily for 6 weeks.
27 Δεκ 2022 · This review is focused on the main indications of the drug, as acute stroke and its sequelae, including the cognitive impairment, and traumatic brain injury and its sequelae. There are retrieved...
These studies claim that citicoline treatment reduces size of infarct (region of dead tissue), decreases free fatty acid concentration, decreases neurologic deficits, restores animal learning performance, reduces glutamate‐mediated injury, preserves phosphatidylcholine levels, and improves neuronal survival (Clark 2009).
This study aims to assess whether starting citicoline treatment within 14 days after stroke onset improves the outcome in patients with acute ischemic stroke, as compared with placebo. Methods: A systematic search was performed to identify all published, unconfounded, randomized, double-blind, and placebo-controlled clinical trials of ...
15 Μαρ 2016 · Citicoline is a drug approved for the treatment of acute ischemic stroke. Although evidence of its efficacy has been reported, recently published results of a large placebo-controlled clinical trial did not show differences.
