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  1. 27 Δεκ 2022 · This review is focused on the main indications of the drug, as acute stroke and its sequelae, including the cognitive impairment, and traumatic brain injury and its sequelae. There are retrieved...

  2. 16 Δεκ 2010 · Fifteen studies on focal ischemia were analyzed describing procedures involving 313 animals and reporting the effect of citicoline on infarct size (n=313) or functional outcome (n=104). The quality of the studies ranged from 0 to 10 based on good laboratory practice recommendations.

  3. 23 Δεκ 2016 · This review is focused on the main indications of the drug, as acute stroke and its sequelae, including the cognitive impairment, and traumatic brain injury and its sequelae. There are retrieved the most important experimental and clinical data in both indications.

  4. 2 Σεπ 2024 · In AD, citicoline administration significantly decreased levels of pro-inflammatory cytokines like MIP-1α, TNFα, IL-1β, and MCP-1 in an in vivo study. The cytidine component of citicoline specifically reduced IL-6, RANTES, and anti-inflammatory cytokine IL-10.

  5. Abstract. Background: Citicoline is a drug approved for the treatment of acute ischemic stroke. Although evidence of its efficacy has been reported, recently published results of a large placebo-controlled clinical trial did not show differences.

  6. 28 Ιουλ 2012 · The primary objective of this study was to assess the effects of citicoline compared with placebo on the recovery of patients with moderate-to-severe acute ischaemic stroke at 3 months, after having received 2000 mg daily for 6 weeks.

  7. Citicoline sodium salt, classified as a nootropic and psychostimulant [1], is an active principle of a variety of prescription drugs, either injectables or oral formulations.

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