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27 Δεκ 2022 · This review is focused on the main indications of the drug, as acute stroke and its sequelae, including the cognitive impairment, and traumatic brain injury and its sequelae. There are retrieved...
23 Δεκ 2016 · This review is focused on the main indications of the drug, as acute stroke and its sequelae, including the cognitive impairment, and traumatic brain injury and its sequelae. There are retrieved the most important experimental and clinical data in both indications.
This study aims to assess whether starting citicoline treatment within 14 days after stroke onset improves the outcome in patients with acute ischemic stroke, as compared with placebo. Methods: A systematic search was performed to identify all published, unconfounded, randomized, double-blind, and placebo-controlled clinical trials of ...
Several studies have suggested that citicoline is effective in treatment of central nervous system disorders (CNS), including acute and chronic cerebral ischemia, intracerebral hemorrhage, global cerebral hypoxia, and neurodegenerative diseases (Martynov 2015).
23 Δεκ 2016 · Band densitometry analysis for PARP by western blotting in different groups of rats in the infarct zone and penumbra zone 12 and 24 h after ischaemia. a p < 0.05; b p < 0.025; c p < 0.0001....
30 Νοε 2022 · Citicoline: pharmacological and clinical review, 2016 update. Rev Neurol 2016; 63 (Supl 3): S1-S73), incorporating 176 new references, having all the information available in the same document to facilitate the access to the inf …
16 Δεκ 2010 · The quality of the studies ranged from 0 to 10 based on good laboratory practice recommendations. Overall, citicoline reduced infarct volume by 28% (95% CI, 19–38; P <0.001), and the reduction was greater in transient ischemia (30%; 95% CI, 15–45) than in permanent ischemia models (25%; 95% CI, 17–33).
