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1 Απρ 2022 · Abstract. Objective: To compare the efficacy and discontinuation of augmentation agents in adult patients with treatment-resistant depression (TRD). We conducted a systematic review and network meta-analyses (NMA) to combine direct and indirect comparisons of augmentation agents.
16-week Comparative Effectiveness Trial of Lamotrigine vs. Fluoxetine for Bipolar Depression Rochester, MN; Austin, MN The FLAME Study is a 16-week clinical trial to study treatment with lamotrigine or fluoxetine in bipolar I, II and bipolar schizoaffective depressed adults.
Eligible adult patients (>18 years of age) had moderate to severe depression and a Patient Health Questionnaire (PHQ-9) 27 score of 10 or higher, no bipolar disorder, an appointment with a member of their primary care team, and no major barriers to providing informed consent.
Let Mayo Clinic researchers know they’re appreciated with a quick message. Look up information about prescription drugs, over-the-counter medications, herbs, vitamins and supplements.
To overcome this problem, we developed the Depression Medication Choice (DMC) encounter decision aid, designed to help patients and clinicians consider the available antidepressants and the extent to which they improved depression and other issues important to patients.
Here, we test citicoline effectiveness as an adjuvant therapy in major depression. Method: A double-blind randomized trial was designed on 50 patients with major depressive disorder who were under treatment with citalopram.
4 Ιαν 2022 · This study assessed its effects on depression compared to selective serotonin reuptake inhibitor medications (or SSRIs). Citicoline improved anxiety and depression (small effect size), but its effects were inferior to those of SSRIs.
