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  1. 16 Νοε 2020 · This study recommends citicoline as a possible protective mediator with therapeutic and antioxidant capability against acute liver failure and HE. Therefore, this drug might be a candidate for attenuating HE adverse effects in clinical settings. However, in the present study, the time of citicoline administration was short.

  2. Citicoline is considered a dietetic source of choline and cytidine. Cytidine does not have any health claim authorized either, but there are claims authorized for choline, concerning its contribution to normal lipid metabolism, maintenance of normal liver function, and normal homocysteine metabolism.

  3. The most frequently presented explanation for the neuroprotective effects of citicoline on the brain is based on the assumption that it is a prodrug which, following injection or ingestion, is sequentially hydrolysed and dephosphorylated, finally, to cytidine (or uridine in humans) and choline.

  4. 27 Δεκ 2022 · This review is focused on the main indications of the drug, as acute stroke and its sequelae, including the cognitive impairment, and traumatic brain injury and its sequelae.

  5. 23 Δεκ 2016 · Citicoline: pharmacological and clinical review, 2010 update. Rev Neurol 2011; 52 (Suppl 2): S1-62-, incorporating 183 new references, having all the information available to facilitate the access to the information in one document.

  6. 1 Νοε 2022 · This study assessed the effects of citicoline treatment and found the drug to accelerate patient arousal and recovery from deficit syndromes, and to improve the quality of survival.

  7. 16 Νοε 2020 · This study recommends citicoline as a possible protective mediator with therapeutic and antioxidant capability against acute liver failure and HE. Therefore, this drug might be a candidate for attenuating HE adverse effects in clinical settings.

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