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1 ημέρα πριν · Contractures in the fingers caused by Dupuytren disease are commonly treated with either limited fasciectomy or injection of collagenase. Evidence to guide the choice of treatment is limited, but ...
27 Ιαν 2022 · Operative treatments include percutaneous needle fasciotomy (PNF), open fasciotomy (OF), Clostridium collagenase histolyticum (CCH) injections, limited fasciectomy (LF) and dermofasciectomy (DF). The various methods of DD treatment are reviewed. Results: We summarize the highlights of each treatment option as well as the strengths and weaknesses.
A systematic review of non-surgical treatments for early-stage Dupuytren’s disease identified various pharmacological treatments (oral, intramuscular, topical or intralesional steroids; vitamin E, furazolidone, aminosyn (an amino acid solution), hyperbaric oxygen), radiotherapy and physical therapies (ultrasound, splinting, frictional massage ...
3 Μαΐ 2022 · Researchers at the Kennedy Institute, University of Oxford, led by Professor Jagdeep Nanchahal have demonstrated the efficacy of the anti-TNF drug adalimumab for patients with early stage Dupuytren’s disease.
29 Απρ 2022 · The consensus is that Dupuytren's disease does not need treatment until contractures develop to greater than 30° at the metacarpophalangeal and 15° at the proximal interphalangeal joint.1 Treatment commonly consists of limited fasciectomy to remove the cord, needle aponeurotomy, or collagenase injection to weaken and break the cord.
A wide range of treatment options for late-stage disease are available, ranging from division of the cords using needle fasciotomy or collagenase injection through to surgical excision of the diseased tissue by limited fasciectomy or dermofasciectomy.
1 Μαΐ 2011 · Treatment for Dupuytren disease was first described by Henry Cline in the late 17th century and involved sectioning the pathologic cords, later known as fasciotomy or aponeurotomy. 4 Since then, surgical intervention traditionally has been the most effective and widely accepted treatment for progressive Dupuytren contractures. 1, 2 Today's ...