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  1. Clinical signs of late septic shock include hypotension, tachycardia with narrow pulse pressure, cold extremities (cold shock), rapid shallow breathing, oliguria, altered level of consciousness, and cyanosis due to pulmonary ventilation perfusion mismatch or underlying pulmonary diseases.

  2. Early clinical signs that indicate septic shock include tachycardia, derangement in temperature (hypothermia or hyperthermia), alteration in mental status and peripheral vasoconstriction (cold shock) or vasodilation (warm shock).

  3. 12 Δεκ 2023 · Advances in understanding sepsis pathophysiology highlight a need to update the definition and diagnostic criteria for pediatric sepsis and septic shock, whereas new data support an increasing role for automated screening algorithms and biomarker combinations to assist earlier recognition.

  4. 13 Ιουν 2024 · The early recognition and initial management of children with or at risk for developing sepsis and septic shock in resource-abundant settings during the critical first hour of resuscitation are reviewed here.

  5. Pediatric specific early recognition screen should include age adjusted vital signs, incorporate high risk conditions, be actionable and forward facing to providers. 2. Consider adding a hard-stop to the screen alert that is actionable (e.g., requires providers to acknowledge the alert and select a management option).

  6. 22 Μαΐ 2024 · Early recognition of sepsis is crucial to ensuring the best outcomes in children and is aided by a working knowledge of the children at particular risk, the common pathogens, and the clinical manifestations.

  7. 19 Σεπ 2024 · Sepsis in children may present initially with non-specific, non-localised symptoms (especially in younger age groups). Therefore it is important to have a low threshold for suspecting sepsis as the initial clinical presentation of sepsis.

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