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28 Ιουν 2023 · Translocation is a genetic abnormality in which part of a chromosome moves to another chromosome. Chromosomes are genetic structures within cells that hold genes. When translocation occurs, it causes flaws in chromosomes, which can lead to serious genetic and health conditions like cancer.
Translocations generate novel chromosomes. In a translocation, a segment from one chromosome is transferred to a nonhomologous chromosome or to a new site on the same chromosome.
21 Ιουλ 2022 · Translocations, in genetics, happen when chromosomes break and the pieces attach to other chromosomes. This mixing of genetic material has important results. The resultant chromosomes are lacking...
In genetics, chromosome translocation is a phenomenon that results in unusual rearrangement of chromosomes. This includes balanced and unbalanced translocation, with two main types: reciprocal , and Robertsonian translocation.
The development of new experimental tools has recently enabled the cell biological delineation of the translocation process. We discuss here how broken chromosomes move, how they find their translocation partners, and how they synapse and then join to form translocations.
5 ημέρες πριν · A translocation, as related to genetics, occurs when a chromosome breaks and the (typically two) fragmented pieces re-attach to different chromosomes. The detection of chromosomal translocations can be important for the diagnosis of certain genetic diseases and disorders.
Translocations are simple “cut and paste” structural genome variants (SVs) that can arise when there are two co-existing breaks on different chromosomes, and the incorrect ends are joined together (i.e. an end from one chromosome is joined to an end from a different chromosome).