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Specific thresholds for ferritin are used to detect iron deficiency and overload in different age groups. The World Health Organization (WHO) estimates that 42% of children less than 5 years of age and 40% of pregnant women worldwide are anaemic.
In addition, individuals with infection (white blood cell counts >10·0 × 10 9 /L) and non-pregnant women with possible liver disease (ALT >70 IU/L or AST >70 IU/L) 16 and inflammation (CRP >5·0 mg/L). 17 The WHO cutoff for severe risk of iron overload is a serum ferritin concentration of more than 150 μg/L for women and girls older than 5 ...
The most commonly used thresholds of serum ferritin concentration to diagnose iron deficiency in studies of iron and/or micronutrient supplementation in pregnant women were <12 μg/L (35 studies) and <15 μg/L (17 studies).
21 Απρ 2020 · This guideline provides global, evidence-informed recommendations on the use of indicators for assessing a population’s iron status and application of the use of ferritin concentrations for monitoring and evaluating iron interventions.
11 Οκτ 2021 · The World Health Organization (WHO) recently recommended ferritin thresholds of less than 15 μg/L (adults) and less than 12 μg/L (children) for the diagnosis of iron deficiency, but these thresholds were based largely on expert opinion along with historical studies correlated with absence of bone marrow iron stores. 1,2
In individuals with infection or inflammation, a ferritin concentration below 30 µg/L in children and 70 µg/L in adults may be used to indicate iron deficiency ( conditional recommendation, 5 low certainty of evidence.
21 Ιουν 2022 · World Health Organization serum ferritin guideline of a <15 µg/L threshold for iron deficiency in healthy women is based on expert opinion. Physiologically based analysis of female blood donors, 20 to 49 years of age, shows a higher ferritin threshold for iron deficiency of <25 µg/L. Abstract.
