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Management of fibrosing mediastinitis. Specialists at Mayo Clinic have used off-label rituximab to treat nearly 30 patients with fibrosing mediastinitis successfully. Disease progression was almost universally halted and two-thirds of the patients improved symptomatically.
Fibrosing mediastinitis (FM), which is also known as mediastinal fibrosis or sclerosing mediastinitis, is an uncommon, benign and progressive condition characterized by an invasive proliferation of fibrous tissue within the mediastinum.
20 Αυγ 2021 · Medical treatments can help address some of the symptoms and complications caused by fibrosing mediastinitis. When fluid retention occurs related to vascular obstructions, patients are treated with diuretic therapy.
14 Δεκ 2019 · Here, we present two cases of young patients with fibrosing mediastinitis complicated by pulmonary artery stenosis requiring medical and endovascular management with excellent results. Keywords: Fibrosing mediastinits, Pulmonary artery stenosis, Pulmonary hypertension
INTRODUCTION: Fibrosing mediastinitis (FM) is a rare, delayed hypersensitivity reaction to a variety of infective or non-infective stimuli that result in a local invasive proliferation of fibrous tissue within the mediastinum.
15 Ιουλ 2014 · Diagnosis can be made rapidly by serological tests, staining, and culture of bronchoalveolar lavage fluid and, in rare cases, biopsy. Therapy with antifungal drugs can result in marked improvement of symptoms. 1 Fibrosing mediastinitis is a rare complication of histoplasmosis.
We conducted the present review of 80 consecutive patients with FM evaluated and treated at Mayo Clinic, Rochester, MN, between 1998 and 2007 to analyze the clinical presentation, radiographic and pathologic findings, therapeutic interventions, and clinical outcomes of the disease.
